Made with BR-DIM diindolylmethane, a phytonutrient found in cruciferous vegetables like Brussels sprouts, broccoli, and cabbage. BR-DIM has been shown to influence estrogen metabolism to increase the ratio of 2-OHE to 16-OHE.* Estrobalance also promotes womens health by increasing the ratio of 2-OHE to 16-OHE, which may have the following benefits: reducing cyclical breast tenderness, promoting breast health, supporting cardiovascular health, and helping to regulate healthy estrogen metabolism.* (Indolplex and BR-DIM is a proprietary, enhanced bioavailability complex containing Diindolylmethane licensed from BioResponse, LLC., Boulder, CO.)*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.