ZADITOR is the original triple-action, prescription-strength formula that works in minutes to deliver up to 12 hours of eye itch relief, by targeting itchy eyes right at the source. And unlike most over-the-counter eye drops, ZADITOR uses only an antihistamine to temporarily relieve itchy eyes and doesnâ€t contain a vasoconstrictor—the stuff that only works temporarily to “get the red out.â€