7C 400mg SAM-e supplements use raw materials containing the highest levels of the active S,S form, manufactured under strictly controlled low-temperature conditions to ensure the biological activity of the product. Each capsule contains 400mg of SAM-e in its active S,S form, derived from 800mg of S-adenosine L-methionine disulfate P-tosylate.
B-vitamins Added to Enhance SAM-e Effectiveness. SAM-e is a metabolite of methionine that requires cofactors to function: vitamin B12 regulates the production of transmethylation reactions of SAM-e, and vitamin B6 regulates the antisulfuration reactions. Deficiencies in these vitamins may reduce SAM-e's efficacy. That's why 7C SAM-e are formulated with vitamin B12/B6 and folic acid, helping SAM-e achieve maximum effectiveness.
Brain Metabolism and Mood. SAM-e methylation reactions are involved in the synthesis of phosphatidylcholine and neurotransmitters like dopamine, norepinephrine, and 5-hydroxytryptamine, which have a positive impact on mood as well as brain metabolism.
Support Joint and Liver Function. SAM-e is effective in promoting the synthesis of proteoglycans, an essential component of connective tissue, thereby increasing joint comfort and mobility. SAM-e also enhances the liver's synthesis of glutathione, an antioxidant that promotes detoxification. This protects liver tissue from a number of toxins.
Enteric-Coated Capsules. 7C SAM-e are enteric-coated capsules that provide slow and targeted release to improve tolerance and absorption in the gastrointestinal tract. This ensures that they are optimally absorbed for maximum benefit.