Thunderstorms & fireworks Traveling, boarding, or kenneling Separation anxiety Routine changes Additional support against daily stress Composure Pro Advanced clinical-strength calming chews for dogs & cats combine five powerful, effective ingredients to promote balanced behavior and focus. Description Directions for Use Our strongest calming aid in the VetriScience Pro Line Composure lineup, these calming chews combine proven, effective ingredients to help address severe behavioral and cognitive issues in both dogs and cats of all sizes and ages. As with our tried-and-true Composure, Pro Advanced is clinically shown to work within 30 minutes and last up to 4 hours.* Composure Pro Advanced is safe to use daily or as-needed. Support pets daily emotional health with the recommended number of chews, or address occasional periods of high stress with Composure Pro Advanced. This vet-formulated calming supplement is safe to double dosage to achieve the desired calming effect. How is Composure Pro Advanced different from Composure Pro or other Composure products? As our most powerful calming formula, Composure Pro Advanced is 1.5x stronger than Composure Pro. It also boasts an additional calming ingredient - Bluenesse lemon balm extract - not found in Composure Pro and our other Composure supplements. Both of these products are recommended for dogs and cats who require support for serious behavioral and cognitive problems. Our classic Composure behavioral health products are recommended for pets who require moderate everyday or occasional support for stressful situations or separation anxiety. Where can I buy VetriScience Composure Pro Advanced? This product is available exclusively through veterinarians. Find a vet near you who sells this and other great VetriScience Pro Line products.ABOUT THE INGREDIENTS: Five powerful active ingredients provide support against pet stress, separation anxiety, and anxious behaviors. Thiamine L-Tryptophan Colostrum Calming Complex Suntheanine L-Theanine Bluenesse Lemon Balm Extract Thiamine, also known as Vitamin B1, can help support the central nervous system, promote a feeling of calm, and reduce occasional stress in dogs and cats. Suntheanine is a patented form of the amino acid l-theanine. Its been shown to promote an alert, focused state without unwanted sluggishness by regulating the release of neurotransmitters in the brain. Colostrum Calming Complex is a proprietary blend of biopeptides that supports stress reduction, brain activity, relaxation, and cognitive function. Its an effective calming agent that may counter the effects of environmental stressors in pets. L-Tryptophan is an essential amino acid precursor used by the body to synthesize behavior-regulating neurotransmitters like serotonin and hormones like melatonin. Tryptophan can be helpful in reducing anxious and aggressive behaviors during times of stress. Bluenesse is a patented form of lemon balm extract which has been shown to improve cognition and mood. Lemon balm also helps to improve the ability to deal with stressors in the environment and promote a balanced temperament. Storage instructions: Store in a cool, dry place. QUALITY-ASSURED SUPPLEMENTS: NASC Quality Certified Made in a Safe Quality Food (SQF) Certified and FDA-Registered Facility Manufactured in the U.S.A. from U.S. & Globally Sourced Ingredients 100% Satisfaction, Money-Back Guarantee No Artificial Flavors No Synthetic Colors or Preservations Veterinarian-Formulated & Recommended *CanCog Technologies Study "Assessment of Anxiolytic Properties of a Novel Compound in Beagle Dogs with a Noise-Induced Model of Fear and Anxiety" Directions for Use: 0-30 lbs: 1/2 chew daily31-60 lbs: 1 chew daily61+ lbs: 2 chews dailyProduct can be given up to two times daily or on an as needed basis. It is safe to double in times of increased stress.