SAMe is a very unstable, hygroscopic compound. The most common delivery form is the coated tablet which includes shellacs, waxes, and plastics containing phthalates- known endocrine disruptors. For years, Metabolic Maintenance has avoided these additives by combining SAMe 200mg with calcium and magnesium to keep it dry, making small batches, constant refrigeration, and a 6 month shelf-life. Now there is an alternative! One of our trusted ingredient partners, Gnosis S.p. A. of Italy, has found a way to combine the SAM e supplement with calcium that makes it shelf-stable at room temperature. We will continue to make small, fresh batches of brain supplements, but we can also pass on to our customers the convenience and savings of regular shipping and storage. SAMe is a critical methyl donor for several important reactions in the body including the formation of healthy levels of neurotransmitters. Other nutrients contribute to the cycle of methylation reactions as well. Our brain support supplement includes calcium and magnesium, to provide an easy-to-take product to support methylation processes in the body. A phthalate-free antioxidants supplement for brain support, liver support, immune health and mood maintenance.