Lactic Acid Bacteria (LAB) are symbiotic bacteria that naturally reside in honey bees' gastrointestinal tract. They serve a multitude of functions and are considered beneficial and completely harmless. LAB is involved in protecting honey from other bacteria, yeasts, and molds, fermentation of beebread, and establishing strong hive immunity against pathogens. In nature, pathogens are always present. A significant number of them gain entry into the hive via pollen and nectar. However, most pathogens are either dead or in spore form. When LAB sense pathogen presence, either live, dead, or as dormant spores, secretion of antimicrobial substances is initiated as a defense. This results in a reduction of pathogens and inhibiting some of the dormant pathogenic spores from germinating. Modern agriculture uses many different pesticides, antibiotics, and other chemicals that cause the honeybee's natural defenses to be severely weakened. This also occurs during Fall winterization when bees are fed sugar water, or if beehives are prophylactically treated with various treatments or antibiotics. SuperDFM-Honeybee contains a combination of LAB, beneficial Bacillus spp., and yeast to diminish disease in bees and brood.