Below is a short description of all the methylated / activated vitamins in Double Wood's Methylated Multivitamin: Riboflavin- 5-Phosphate is the "activated" or "usable" coenzyme form of Riboflavin that is more readily usable by the body. It is a coenzyme that plays a major role in energy production, healthy methylated, cellular function, growth, development, and metabolism. Pyridoxal-5-Phosphate (P5P)(PLP) is the "activated" or "usable" coenzyme form of Vitamin B6 and is considered to be the best form of Vitamin B6 for this reason. It is a coenzyme that is important for health methylation and is the co-factor for all transaminase enzymes which transforms one amino acid into another amino acid. It plays an important role in energy production and gluconeogenesis. Calcium L-5-methyltetrahydrofolate (L-5-MTHF) is methylated folic acid. Folic acid itself is inactive in the human body but L-5-MTHF is already activated and usable by the human body and is much more effective at supporting folate levels. Methyl cobalamin is the methylated or "activated" coenzyme form of Vitamin B12 that is already bioavailable and usable by your body. This is the best form of Vitamin B12 for supporting Vitamin B12 levels in the body. Dibencozide (also known as Adenosylcobalamin) is another "activated" form of Vitamin B12 that is also a coenzyme. It may help the body process protein and support cognitive function. Trimethylglycine (TMG) is a methylated amino acid that helps the body metabolize am amino acid called homocysteine.