When taking Bio-35 "Give your body time" It takes years for the cumulative effects of physical, emotional and chemical stress to take their toll on the body. A common mistake is not taking enough Bio-35 during the first few months. To receive the best results from Bio35 take 1-2 capsules in the morning and 1 capsule in the evening. You don't have to take with food, but most people find they prefer to take with food. In 2-3 months you should start to notice a difference in how you feel. (We would like to share with you some of the benefits you should start to notice, but due to FDA regulations we can not list them.) Read the reviews for both the possitive and neg from our customvers. Store your Bio35 soft gels at room temp in a cupboard or counter top out of the sun. Do not refrigerate or keep in high humidity areas like a bathroom.