The multiple-button hoist control lockout effectively prevents users from operating hoist controls, such as those commonly used to operate cranes. The device consists of two components, a 5" x 12" plastic pipe insert, and a 9" x 18" fabric cover. The cover features an enclosed leather belt that accepts up to 6 padlocks. The pipe fits around the hoist controls, which is then covered by the fabric pouch and locked out.