Calmoseptine ointment is a moisture barrier ointment that contains calamine, zinc oxide, menthol, and lanolin. Originally designed to treat diaper rash, Calmoseptine ointment has successfully been used to treat incontinence sites, feeding tube site leakage, wound drainage, minor cuts and scrapes, minor burns, fecal. Calmoseptine ointment acts as a barrier to protect the skin and draw away moisture. By creating this barrier the Calmoseptine ointment relieves discomfort and itching.