Berberine is a bioactive plant extract with thousands of years of historical use in Ayurvedic and Chinese medicine. It is referred to as a ‘pleiotropic,' meaning that it influences the activity of many body systems. Berberine has been shown to be effective in supporting gut health, metabolism, and many biochemical pathways related to longevity and healthy aging. The ProHealth formula contains BioPerine to help increase bioavailability. Plus, it also contains Ceylon Cinnamon that has been historically used for the support of healthy metabolic function. Disclaimer: These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. - - References: 1. Zhao JV et al. Nutrients. 2021;13(8):2550. 2. Gasmi A et al. Curr Med Chem. 2024;31(10):1214-1234. 3. Neag MA et al. Front Pharmacol. 2018;9:557. 4. Imenshahidi M, Hosseinzadeh H. Phytother Res. 2019;33(3):504-523. 5. Li M, Zhang H, Zhang Y, et al. J Immunol. 2022;208(10):2309-2318. 6. Dong C et al. Biomedicine & Pharmacotherapy. 2021;139(7):111595.