Trigonelline is a unique NAD+ precursor that can survive through the acid and enzymes of the digestive process to be absorbed into the bloodstream intact. Since it is so highly bioavailable, it can be delivered to tissues throughout the body and absorbed into cells to be utilized in the synthesis of NAD+ using the Preiss-Handler pathway, while other NAD+ precursors primarily use the Salvage pathway.

By directly impacting NAD+ synthesis in tissues throughout the body, Trigonelline can protect youthful function of organ systems like the brain and the heart, supporting cognition and circulation. It can also protect skeletal muscle strength as well as regulation of healthy blood lipid and sugar metabolism.

Renue By Science has been driving longevity research forward since its foundation, and continues to innovate with novel molecules and the most effective delivery systems. Each batch of every product is rigorously tested by third-party labs and backed by clinical research to provide quality and effectiveness that isn't available anywhere else.