Stop the itchsanity! Cortizone-10 Maximum Strength Water Resistant Anti-Itch Ointment works fast to relieve itch and inflammation associated with eczema; psoriasis; poison oak, ivy, and sumac; and other minor skin irritations. It's formulated with maximum-strength hydrocortisone to help relieve itch in under 10 minutes. Cortizone-10 Ointment is also made with petrolatum, which creates a water-resistant barrier on skin while it locks in moisture. Best of all, this anti-itch ointment is fragrance free and dye free. No wonder it's the No. 1 doctor-recommended anti-itch brand among topical analgesics.* *2021 IQVIA Study.