Stop the itchsanity! Cortizone-10 Maximum Strength Overnight Anti-Itch Cream works fast to relieve itch while you sleep. Made with maximum-strength hydrocortisone, this anti-itch cream features lavender scent and melatonin for a calming experience while you sleep. Use it on itch and inflammation associated with eczema; psoriasis; poison oak, ivy, and sumac; and other minor skin irritations. Best of all, this anti-itch cream contains 10 moisturizers and two vitamins to hydrate and nourish skin. It's even safe for sensitive skin when used as directed. No wonder it's the No. 1 doctor-recommended anti-itch brand among topical analgesics.* *2021 IQVIA Study