Preparation H Soothing Relief Anti Itch Cream is a 1% hydrocortisone cream that provides maximum strength itch relief without a prescription to keep you comfortable day and night. Featuring a smooth, fragrance free formula, this itch relief cream is pleasant and easy to use up to four times daily as a anal itching treatment. When itchy butt strikes, reach for maximum strength relief from the experts in butt care and hemorrhoid itch treatment, Preparation H. Using Preparation H Soothing Relief Cleansing and Cooling Wipes before applying this butt itch cream helps to cool, soothe and cleanse before treating itching.