Eggshell membrane is a unique biological matrix that is composed of major joint constituents, including chondroitin, glucosamine, hyaluronic acid, collagen, and other proteins. NEM is a patented eggshell membrane preparation that can help to maintain healthy articular cartilage and surrounding synovial tissue by nourishing joints, as well as by supporting a balanced immune response to typical daily wear and tear.* Clinical studies demonstrate that NEM can help to promote normal joint comfort and flexibility, usually within 7-10 days.* NEM is a registered trademark of ESM Technologies, LLC and is registered in the United States and other countries. Natural color variation may occur in this product.