Niacin is usually processed and eliminated by the body within an estimated 2-4 hour range. Our high potency, timed release niacin (Vitamin B3) is formulated in a special base that provides a gradual release of the niacin over a period of several hours. This provides the body an extended source of niacin availability to the body over several hours before being completed eliminated from the system. Our Niacin Time Release formula also minimizes flushing.