Rugby Stimulant Laxative Plus Stool Softener Docusate Sodium 50 mg / Sennosides 8.6 mg - 1000 Tablets. Compare the active ingredient in the leading 2 in 1 brand. Relieves occasional constipation (irregularity). Generally produces a bowel movement in 6 to 12 hours. Docusate sodium and sennosides are two different medications that are often combined to treat constipation. Docusate sodium is a stool softener that works by drawing water into the stool, making it softer and easier to pass. Sennosides, on the other hand, are a type of laxative that work by stimulating the muscles in the intestines to move stool along. The combination of docusate sodium and sennosides can be beneficial for people who have constipation that is caused by a variety of factors, such as a low-fiber diet, dehydration, or certain medications. By softening the stool and stimulating bowel movements, these medications can help relieve constipation and promote regularity. However, it's important to note that these medications should be used only as directed and under the guidance of a healthcare professional. Overuse or misuse of laxatives can lead to dependence and other complications. Additionally, some people may experience side effects such as diarrhea, cramping, or nausea when using these medications.