B12 deficiency is more common than you'd think! When you're feeling a little low on your Bs, Buzzy B12 is here to give you a healthy boost of plant-based bioactive B12 at an affordable price! B12 can be hard to get through a plant-based diet, and not everyone has the genes needed to absorb and methylate B12 efficiently. Gastrointestinal issues and anemia can also lead to lower B12 levels. Why does B12 matter so much? B12 deficiency has been associated with: Tiredness, depression, impaired cognitive health and function, and increased homocysteine levels, which can increase the risk of heart and cardiovascular complications.