Size:200ct Caplets Excedrin Extra Strength headache medicine has a fast-acting formula that delivers powerful relief from headache symptoms. For some, headache relief starts in just 15 minutes. With 2 pain fighters and an amplifier, Excedrin Extra Strength helps you fight headaches, fast. Excedrin Extra Strength's combination of active ingredients, acetaminophen, aspirin and caffeine, offer a fast-acting, non-prescription headache pain reliever alternative. It's a headache treatment that relieves minor aches and pains due to headache, cold, arthritis, muscular aches, toothache and premenstrual and menstrual cramps. Adults and children 12 years and over: Take 2 tablets every 6 hours; not more than 8 tablets in 24 hours. Children under 12 years: Ask a doctor.